Epigenomics AG (OJ:ECX) Epigenomics AG / Voting rights: Voting Rights: Release of a Voting Rights Notification (§ 21 para. 1 WpHG) in Accordance with § 26, para. 1 WpHG (German Securities Trading Act) with the Aim of an Europe-wide Distribution Publication pursuant to §26 sect.1 WpHG (the German Securities Trading Act) processed and transmitted by Hugin. The issuer is solely responsible for the content of this announcement. ---------------------------------------------------------------------- --------------



Issuer:

Epigenomics AG - ISIN DE000A0BVT96 - Kleine Präsidentenstr. 1 10178 Berlin Deutschland

Voting Rights Notification:

On 10 September 2008 Federated Investors Inc., Pittsburgh, PA, USA made the following notifications regarding the holding of voting rights held in Epigenomics AG, Berlin, Germany, according to § 21 WpHG in their name as well as for Federated Equity Management Company of Pennsylvania, Pittsburgh, PA, USA:

Notification of voting rights in the name and on behalf of Federated Equity Management Company of Pennsylvania pursuant to § 21 para. 1 WpHG:

On 8 September 2008 Federated Equity Management Company of Pennsylvania exceed the 20 per cent threshold of § 21 para. 1 WpHG and held at this date 20.125 per cent of the voting rights (5,375,319 voting rights) in Epigenomics AG.

As of 8 September 2008 Federated Equity Management Company of Pennsylvania held 20.125 per cent of the voting rights (5.375.319 voting rights) in Epigenomics AG. All 20.125 per cent of the voting rights (5.375.319 voting rights) are attributed to Federated Equity Management Company of Pennsylvania pursuant to § 22 para. 1 sent. 1 no. 6 WpHG. Some of the voting rights are attributed to Federated Equity Management Company of Pennsylvania by Federated Kaufmann Fund which holds directly 3 per cent or more of the voting rights in Epigenomics AG.

Federated Investors Inc. are the parent company of F II Holdings Inc., which in turn is the parent company of Federated Equity Management Company of Pennsylvania. Federated Equity Management Company of Pennsylvania, an investment adviser registered in the United States under the Investment Company Act of 1940, acts as Investment Adviser to the Federated Kaufmann Fund and Federated Kaufmann Fund II, both Massachusetts Business Trusts and Investment Companies, as that term is defined under the Investment Company Act 1940, as amended.

Date of release: 11. September 2008

Epigenomics AG The Executive Board

Contact: Epigenomics AG Dr. Achim Plum Sr. Vice President Corporate Development Tel.: +49 (0)30 24345 368 Fax: +49 (0)30 24345 555 Email: achim.plum@epigenomics.com

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Epigenomics AG Kleine Präsidentenstr.1 Berlin Germany

WKN: A0BVT9; ISIN: DE000A0BVT96; Index: CDAX, Prime All Share, TECH All Share; Listed: Amtlicher Markt in Frankfurter Wertpapierbörse, Prime Standard in Frankfurter Wertpapierbörse, Freiverkehr in Börse Berlin, Freiverkehr in Börse Düsseldorf, Freiverkehr in Hanseatische Wertpapierbörse zu Hamburg, Freiverkehr in Bayerische Börse München, Freiverkehr in Börse Stuttgart;

Epigenomics AG

http://www.epigenomics.de

ISIN: DE000A0BVT96

Stock Identifier: XFRA.ECX

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