Actelion Pharmaceuticals Ltd (OTC:ALIOF) Corporate news announcement processed and transmitted by Hugin ASA. The issuer is solely responsible for the content of this announcement. ---------------------------------------------------------------------- --------------



ALLSCHWIL, SWITZERLAND - 8 July 2008 - Actelion Ltd (SWX: ATLN) announced today that the Management Committee of the SWX Swiss Exchange has decided to add Actelion shares (ATLN, CH001053248) to the Swiss Market Index SMI®. Actelion shares will trade for the first time as part of the SMI on Monday, 22nd September 2008, when the SMI basket adjustment will take place.

As a blue-chip index, the SMI is Switzerland's key equity index. It represents about 85% of the free-float capitalization of the Swiss equity market. The SMI comprises the 20 largest and most liquid equities of the SPI® (Swiss Performance Index®). Since the SMI is considered to be a mirror of the overall Swiss stock market, it is used as the underlying index for numerous derivative financial instruments such as options, futures and index funds (e.g. ETFs).

The composition of the SMI is examined - and - if appropriate - updated once a year. More details about the index, the selection process and past, current and future composition of the index are available on the website of the SWX Swiss Exchange at www.swx.com

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Actelion Ltd Actelion Ltd is a biopharmaceutical company with its corporate headquarters in Allschwil/Basel, Switzerland. Actelion's first drug Tracleer®, an orally available dual endothelin receptor antagonist, has been approved as a therapy for pulmonary arterial hypertension. Actelion markets Tracleer® through its own subsidiaries in key markets worldwide, including the United States (based in South San Francisco), the European Union, Japan, Canada, Australia and Switzerland. Actelion, founded in late 1997, is a leading player in innovative science related to the endothelium - the single layer of cells separating every blood vessel from the blood stream. Actelion's over 1700 employees focus on the discovery, development and marketing of innovative drugs for significant unmet medical needs. Actelion shares are traded on the SWX Swiss Exchange (ticker symbol: ATLN).

For further information please contact: Roland Haefeli Vice President, Head of Investor Relations & Public Affairs Actelion Pharmaceuticals Ltd, Gewerbestrasse 16, CH-4123 Allschwil +41 61 565 62 62 +1 650 624 69 36 http://www.actelion.com

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Actelion Pharmaceuticals Ltd Gewerbestrasse 16 Allschwil Switzerland

WKN: 936767; ISIN: CH0010532478; Index: SBIOM, SLIFE, SMCI, SMIEXP, SMIM, SPI, SPIEX; Listed: Main Market in SWX Swiss Exchange;



LINK: http://hugin.info/131801/R/1234505/262966.pdf

Actelion Pharmaceuticals Ltd

http://www.actelion.com

ISIN: CH0010532478

Stock Identifier: XSWX.ATLN

US: OTC:ALIOF

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